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International Journal of Hypertension
Volume 2015, Article ID 615681, 5 pages
Review Article

Sleep Deficiency and Deprivation Leading to Cardiovascular Disease

1Stern College for Women, Yeshiva University, New York, NY 10016, USA
2Department of Cardiology, North Shore-LIJ Health System, Hofstra North Shore-LIJ School of Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA

Received 22 November 2014; Revised 13 May 2015; Accepted 19 May 2015

Academic Editor: Markus P. Schlaich

Copyright © 2015 Michelle Kohansieh and Amgad N. Makaryus. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sleep plays a vital role in an individual’s mental, emotional, and physiological well-being. Not only does sleep deficiency lead to neurological and psychological disorders, but also the literature has explored the adverse effects of sleep deficiency on the cardiovascular system. Decreased quantity and quality of sleep have been linked to cardiovascular disease (CVD) risk factors, such as hypertension, obesity, diabetes, and dyslipidemia. We explore the literature correlating primary sleep deficiency and deprivation as a cause for cardiovascular disease and cite endothelial dysfunction as a common underlying mechanism.