CYP17A1 and Blood Pressure Reactivity to Stress in Adolescence
Table 1
Basic characteristics and studied BP phenotypes.
Males
Females
Estimated difference (95% CI)
value
(A) Basic characteristics*
Age (years)
14.4 ± 1.8
14.6 ± 1.9
0.2 (−0.1–0.4)
0.15
Height (cm)
166.8 ± 10.7
159.6 ± 6.7
7.6 (6.7–8.6)
<0.0001
Body weight (kg)
61.3 ± 16.9
56.0 ± 12.6
0.9 (−0.7–2.5)
0.29
BMI (kg/m2)
21.8 ± 4.6
21.9 ± 4.4
0.02 (−0.5–0.6)
0.94
(B) SBP, mm Hg†
Prestanding
118.7 ± 12.8
120.1 ± 11.3
1.4 (−0.2–3.1)
0.09
Standing
129.6 ± 15.4
129.0 ± 13.5
0.6 (−1.4–2.6)
0.53
Reactivity to standing
11.1 ± 9.8
8.8 ± 9.2
2.3 (1.0–3.6)
0.0007
Premath stress
122.6 ± 14.2
119.7 ± 13.0
2.9 (1.0–4.8)
0.002
Math stress
140.4 ± 16.3
136.2 ± 14.6
4.3 (2.2–6.4)
<0.0001
Reactivity to math stress
18.2 ± 10.6
16.7 ± 10.6
1.5 (0–3.0)
0.05
Poststanding restingc
123.2 ± 13.6
120.0 ± 11.8
3.1 (1.4–4.9)
0.0004
Postmath restingc
127.3 ± 13.1
124.8 ± 12.5
2.6 (0.8–4.3)
0.004
(C) DBP, mm Hg†
Prestanding
70.3 ± 8.1
68.4 ± 7.4
1.9 (0.8–3.0)
0.0006
Standing
80.4 ± 11.1
78.8 ± 10.1
1.6 (0.1–3.1)
0.03
Reactivity to standing
10.4 ± 5.9
10.2 ± 5.8
0.2 (−0.7–1.0)
0.69
Premath stress
78.7 ± 9.6
76.1 ± 9.2
2.6 (1.3–3.9)
0.0001
Math stress
89.0 ± 11.4
86.6 ± 10.6
2.4 (0.8–3.9)
0.002
Reactivity to math stress
10.4 ± 5.8
10.6 ± 6.0
0.2 (−0.7–1.0)
0.67
Poststanding restingc
78.9 ± 9.6
76.1 ± 9.0
2.8 (1.5–4.1)
<0.0001
Postmath restingc
81.9 ± 9.7
79.8 ± 8.9
2.2 (0.9–3.5)
0.001
Nonadjusted means ± standard deviations are shown. The differences between males and females are given, adjusted for age and, when appropriate, height. †Means adjusted for age and height ± standard deviations are shown. The differences between males and females are given, adjusted for age and height.
cResting SBP/DBP is a 5-minute average of SBP/DBP measured while seated after 5 minutes at rest. CI = confidence interval.
