Genetic Variants of C-5312T REN Increased Renin Levels and Diastolic Blood Pressure Response to Angiotensin Receptor Blockers

Table 5

Genetic variants of the REN and reduction in blood pressure (telmisartan therapy).

REN C-5312T	SBP (mmHg)			DBP (mmHg)
	Baseline	ARB		Baseline	ARB
CT/TT	150.5 ± 18.4	130.5 ± 13.6	0.66	90.20 ± 15.5	82.2 ± 15.4	0.03
CC	145.7 ± 17.9	125 ± 20.5		92.45 ± 15.23	80.1 ± 15.6

Data are means ± SD. Statistical analysis of the difference was performed by independent -test as appropriate. value was calculated for the statistics showing the interactive effect of ARB administration and category in patients on DBP.