International Journal of Hypertension / 2016 / Article / Tab 3

Research Article

The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 3

Comparison of treated (taking antihypertensive medications) PWH and NHANES subjects.
(a)

VariableNHANESPWH
Median (IQR)Median (IQR)

Systolic BP (mmHg)127 (119–140)539134 (126–141)118<0.001
Diastolic BP (mmHg)76 (67–83)53984 (76–89)118<0.001
BMI (kg/m2)30.6 (27.3–35.0)53427.7 (24.8–31.0)115<0.001
Creatinine (mg/dL)0.99 (0.86–1.12)5080.90 (0.80–1.10)1160.007
eGFR (mL/min/1.73 m2)89 (73–101)50898 (74–108)1160.005
Cholesterol (total) (mg/dL)186 (160–214)509164 (137–193)85<0.001

(b)

VariableNHANESPWH
(%) (%)

HIVPositive2 (0.7)33 (29.5)<0.001
Negative281 (99.3)79 (70.5)
HCVPositive17 (13.4)91 (81.3)<0.001
Negative491 (96.7)21 (18.8)
DiabetesPositive178 (33.0)31 (26.3)0.188
Negative361 (67.0)87 (73.7)
SmokingCurrent109 (20.2)16 (18.6)0.166
Former192 (35.6)23 (26.7)
Never238 (44.2)47 (54.7)

NHANES indicates subjects from the National Health and Nutrition Examination Survey of the general United States population; PWH, patients with hemophilia; IQR, interquartile range; BP, blood pressure; BMI, body mass index; eGFR, estimated glomerular filtration rate; and HCV, hepatitis C virus.