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International Journal of Hypertension
Volume 2018, Article ID 1691474, 7 pages
https://doi.org/10.1155/2018/1691474
Research Article

Association between CD4 Cell Count and Blood Pressure and Its Variation with Body Mass Index Categories in HIV-Infected Patients

1Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
2Department of Orthopaedics, Southend University Hospital, Essex, UK
3Health and Human Development (2HD) Research Network, Douala, Cameroon
4Presbyterian General Hospital Acha-Tugi, Acha-Tugi, Cameroon
5Grace Community Health and Development Association (GRACHADA), Kumba, Cameroon
6Department of Vascular Surgery, Ashford and St Peter’s Hospitals NHS, Surrey, UK
7Department of Public Health, Université libre de Bruxelles, Brussels, Belgium
8Diabetes and Endocrinology Unit, Department of Internal Medicine, Douala General Hospital, Douala, Cameroon
9Department of Internal Medicine and Paediatrics, Faculty of Health Sciences, University of Buea, Buea, Cameroon

Correspondence should be addressed to Christian Akem Dimala; ku.ca.mthsl.inmula@1alamid.meka.naitsirhc

Received 25 June 2017; Revised 1 November 2017; Accepted 19 December 2017; Published 22 January 2018

Academic Editor: Daniel Duprez

Copyright © 2018 Christian Akem Dimala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to establish whether an independent relationship exists between CD4 count and hypertension and if this relationship is modified or confounded by the body mass index (BMI). Methods. A secondary data analysis of a cross-sectional study on 200 HIV/AIDS patients at a referral hospital in Cameroon was conducted. Linear and logistic regression models were used as appropriate to explore the association between the variables of interest. Results. There was no linear association between log CD4 count and both systolic (; ) and diastolic blood pressures (; ), respectively. After adjusting for BMI, patients with CD4 count ≥ 350 cells/μl were more likely to have hypertension than those with CD4 count < 350 cells/μl (AOR: 2.50, 95% CI: 1.05–5.93, and ). There was no effect modification from BMI (test of homogeneity, ). There was no independent relationship between CD4 count and hypertension after controlling for age, sex, family history of hypertension, BMI-defined overweight, HAART use, and duration of HIV infection (AOR: 1.66, 95% CI: 0.48–5.71, and ). Conclusion. This study did not identify any independent relationship between CD4 count and hypertension. Large prospective studies are recommended to better explore this relationship between hypertension and CD4 count.