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International Journal of Hypertension
Volume 2018, Article ID 5952021, 7 pages
https://doi.org/10.1155/2018/5952021
Research Article

Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana

1Division of Clinical Sciences, Renal Medicine, St George’s, University of London, Cranmer Terrace, London SW17 0RE, UK
2School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
3Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 58 Turner Street, London E1 2AB, UK
4Department of Medicine, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
5Department of Paediatrics, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
6Division of Health Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry CV4 &AL, UK

Correspondence should be addressed to Jacob Plange-Rhule; moc.liamg@eluhrpj

Received 1 November 2017; Revised 21 February 2018; Accepted 5 March 2018; Published 5 April 2018

Academic Editor: Franco Veglio

Copyright © 2018 Jacob Plange-Rhule et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hypertension is the most important risk factor for cardiovascular mortality and morbidity in Sub-Saharan Africa. In western populations, high haemoglobin levels are associated with raised BP unlike in Sub-Saharan Africa where there is a paucity of data. Our study examines the association between haematological indices with BP variables. Weight, height, BP, and whole blood indices of viscosity (Hb, haematocrit, RBC count, and MCV) were measured in 921 adults (340 men, 581 women; aged 40–75) in 12 communities in Ghana. Mean values for Hb (12.3 g/dl ± 1.7 SD), haematocrit (), RBC (4.10 million/μL ± 0.64), and MCV were lower than reference values used in Sub-Saharan Africa. Mean BMI was indicating a lean population. Systolic BP increased by 1.0 mmHg (95% CI 0.5–1.5), , for women and 0.5 (0.1–1.0), , for men per unit increase in haematocrit. Similar relationships were found for Hb and RBC but not for MCV or platelets. The relationships were weaker when adjusted for BMI, 0.7 mmHg (0.2–1.2) in women and 0.5 (0.0–1.0) in men. Findings for diastolic BP were similar. Overall haematological indices were low. We have found a significant, positive relationship between BP, Hb, Haematocrit, and RBC count in our population.