Research Article

Early- and Late-Onset Preeclampsia: A Comprehensive Cohort Study of Laboratory and Clinical Findings according to the New ISHHP Criteria

Table 3

The revised ISSHP criteria of preeclampsia [8, 9] in women with singleton pregnancy and early- or late-onset preeclampsia.

CriterionEOP (n = 113)LOP (n = 101)Total (n = 214)

Proteinuria113 (100.0)101 (100.0)214 (100.0)ns
Renal insufficiency (creatinine >90 μmol/L), n (%)11 (9.7)6 (6.0)17 (7.9)ns
Liver involvement, n (%)15 (13.3)8 (7.9)23 (10.7)ns
Neurological complications, n (%)20 (17.7)8 (8.0)28 (13.0)0.0342
Hematological complications, n (%)50 (44.2)35 (34.6)85 (39.7)ns
(i) Thrombocytopenia, n (%)37 (74)29 (82.8)66 (77.6)ns
(ii) DIC, n (%)0 (0.0)2 (5.8)2 (2.4)ns
(iii) Hemolysis, n (%)13 (26)4 (11.4)17 (20.0)0.0416
FGR, n (%)80 (70.7)49 (48.5)129 (60.3)0.0009

DIC, disseminated intravascular coagulation; EOP, early-onset preeclampsia; FGR, fetal growth restriction; ISSHP, International Society for the Study of Hypertension in Pregnancy; LOP, late-onset preeclampsia; ns, nonstatistically significant.