Clinical Study

Effect of Nebivolol and Olmesartan on 24-Hour Brachial and Aortic Blood Pressure in the Acute Stage of Ischemic Stroke

Table 1

Baseline, demographic, clinical, and laboratory characteristics of study participants.

ParameterOverall Nebivolol (5 mg/day) Olmesartan (20 mg/day) No-treatment value

Age (years)79.3 ± 8.280.7 ± 7.379.5 ± 9.577.7 ± 7.80.51
Male gender (, %)22 (36.7)5 (25.0)6 (30.0)11 (55.0)0.11
Body weight (kg)73.3 ± 9.675.2 ± 11.370.5 ± 7.574.2 ± 9.70.27
Height (m)1.66 ± 0.11.65 ± 0.11.66 ± 0.11.68 ± 0.10.46
BMI (kg/m2)26.5 ± 3.527.5 ± 3.825.5 ± 3.626.4 ± 3.10.21
History of DM (, %)24 (40.0)7 (35.0)5 (25.0)12 (60.0)0.07
History of hypertension (, %)44 (73.3)13 (65.0)16 (80.0)15 (75.0)0.55
History of CAD (, %)11 (18.3)5 (25.0)3 (15.0)3 (15.0)0.36
History of previous stroke (, %)14 (23.3)6 (30.0)2 (10.0)6 (30.0)0.19
24-h brachial SBP (mmHg)153.1 ± 16.9153.4 ± 19.1151.7 ± 14.0154.3 ± 18.20.89
24-h brachial DBP (mmHg)84.4 ± 9.983.1 ± 9.284.7 ± 7.585.4 ± 12.80.76
Serum urea (mg/dl)45.8 ± 15.846.3 ± 17.745.5 ± 13.345.6 ± 16.9>0.90
Serum creatinine (mg/dl)1.1 ± 0.21.1 ± 0.31.0 ± 0.21.1 ± 0.20.84
Uric acid (mg/dl)4.9 ± 1.34.9 ± 1.15.0 ± 1.74.7 ± 1.30.72
Total cholesterol (mg/dl)173.4 ± 44.5160.8 ± 41.1190.6 ± 39.3168.9 ± 48.80.09
HDL cholesterol (mg/dl)46.7 ± 11.844.4 ± 9.450.5 ± 13.545.4 ± 11.80.21
LDL cholesterol (mg/dl)113.9 ± 39.3104.5 ± 33.1118.1 ± 35.2119,1 ± 48.20.43
Triglycerides (mg/dl)121.8 ± 44.0112.2 ± 43.7121.6 ± 46.3131.6 ± 42.00.38

BMI = body mass index; CAD = coronary artery disease; DM = diabetes mellitus; DBP = diastolic blood pressure; HDL = high-density lipoprotein; LDL = low-density lipoprotein; SBP = systolic blood pressure; data are presented as mean ± SD or absolutes frequencies and percentages.