Clinical Study
Effect of Nebivolol and Olmesartan on 24-Hour Brachial and Aortic Blood Pressure in the Acute Stage of Ischemic Stroke
Table 1
Baseline, demographic, clinical, and laboratory characteristics of study participants.
| Parameter | Overall | Nebivolol (5 mg/day) | Olmesartan (20 mg/day) | No-treatment | value |
| Age (years) | 79.3 ± 8.2 | 80.7 ± 7.3 | 79.5 ± 9.5 | 77.7 ± 7.8 | 0.51 | Male gender (, %) | 22 (36.7) | 5 (25.0) | 6 (30.0) | 11 (55.0) | 0.11 | Body weight (kg) | 73.3 ± 9.6 | 75.2 ± 11.3 | 70.5 ± 7.5 | 74.2 ± 9.7 | 0.27 | Height (m) | 1.66 ± 0.1 | 1.65 ± 0.1 | 1.66 ± 0.1 | 1.68 ± 0.1 | 0.46 | BMI (kg/m2) | 26.5 ± 3.5 | 27.5 ± 3.8 | 25.5 ± 3.6 | 26.4 ± 3.1 | 0.21 | History of DM (, %) | 24 (40.0) | 7 (35.0) | 5 (25.0) | 12 (60.0) | 0.07 | History of hypertension (, %) | 44 (73.3) | 13 (65.0) | 16 (80.0) | 15 (75.0) | 0.55 | History of CAD (, %) | 11 (18.3) | 5 (25.0) | 3 (15.0) | 3 (15.0) | 0.36 | History of previous stroke (, %) | 14 (23.3) | 6 (30.0) | 2 (10.0) | 6 (30.0) | 0.19 | 24-h brachial SBP (mmHg) | 153.1 ± 16.9 | 153.4 ± 19.1 | 151.7 ± 14.0 | 154.3 ± 18.2 | 0.89 | 24-h brachial DBP (mmHg) | 84.4 ± 9.9 | 83.1 ± 9.2 | 84.7 ± 7.5 | 85.4 ± 12.8 | 0.76 | Serum urea (mg/dl) | 45.8 ± 15.8 | 46.3 ± 17.7 | 45.5 ± 13.3 | 45.6 ± 16.9 | >0.90 | Serum creatinine (mg/dl) | 1.1 ± 0.2 | 1.1 ± 0.3 | 1.0 ± 0.2 | 1.1 ± 0.2 | 0.84 | Uric acid (mg/dl) | 4.9 ± 1.3 | 4.9 ± 1.1 | 5.0 ± 1.7 | 4.7 ± 1.3 | 0.72 | Total cholesterol (mg/dl) | 173.4 ± 44.5 | 160.8 ± 41.1 | 190.6 ± 39.3 | 168.9 ± 48.8 | 0.09 | HDL cholesterol (mg/dl) | 46.7 ± 11.8 | 44.4 ± 9.4 | 50.5 ± 13.5 | 45.4 ± 11.8 | 0.21 | LDL cholesterol (mg/dl) | 113.9 ± 39.3 | 104.5 ± 33.1 | 118.1 ± 35.2 | 119,1 ± 48.2 | 0.43 | Triglycerides (mg/dl) | 121.8 ± 44.0 | 112.2 ± 43.7 | 121.6 ± 46.3 | 131.6 ± 42.0 | 0.38 |
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BMI = body mass index; CAD = coronary artery disease; DM = diabetes mellitus; DBP = diastolic blood pressure; HDL = high-density lipoprotein; LDL = low-density lipoprotein; SBP = systolic blood pressure; data are presented as mean ± SD or absolutes frequencies and percentages.
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