High Efficiency and Problems of Chemiluminescence Assay-Detected Aldosterone-To-Renin Ratio in Practical Primary Aldosteronism Screening

Table 1

Baseline characteristics.

Variable	Cohort (n = 238)	value
Sample (cases)
PA	58
Non-PA	180
Gender (cases)		0.556
Male	127
PA	29
Non-PA	98
Female	111
PA	29
Non-PA	82
Age (years)^a		0.148
PA	48.59 ± 11.25 (28–72)
Non-PA	45.83 ± 15.96 (12–86)
Total	46.50 ± 14.97 (12–86)
Aldosterone concentration (pg/ml)^b		<0.001
PA	337.35 (61.52–2080.67)
Non-PA	219.02 (55.78–990.20)
Total	235.66 (55.78–2080.67)
Renin concentration (pg/ml)^b		<0.001
PA	5.55 (0.10–353.70)
Non-PA	18.30 (2.10–146.40)
Total	14.20 (0.10–353.70)
ADRR^b		<0.001
PA	70.12 (2.83–615.20)
Non-PA	13.36 (0.97–149.72)
Total	16.62 (0.97–615.20)
Creatinine concentration (μmol/L)^b		0.415
PA	73.5 (42–741)
Non-PA	71.0 (34–1677)
Total	71.0 (34–1677)
PA classification (cases)
Aldosteronoma	24
Adrenal cortical hyperplasia	9
Idiopathic hyperaldosteronism	11
Aldosteronoma and adrenal cortical hyperplasia	2
Unidentified	12

PA: primary aldosteronism; ALD: aldosterone; ADRR: aldosterone-to-renin ratio; ^anormally distributed data are presented as mean ± SD (range); ^bdata without normal distribution are given as median (range).