Magnesium Lithospermate B Downregulates the Levels of Blood Pressure, Inflammation, and Oxidative Stress in Pregnant Rats with Hypertension

Figure 4

MLB rescued levels of VEGF and NO. (a) Representative immunoblot analysis together with relative protein expression of VEGF in placentas of each group (n = 10). (b) Relative mRNA expression of VEGF in placentas of each group (n = 10). (c) Representative immunoblot analysis together with relative protein expression of eNOS in placentas of each group (n = 10). (d) Relative expression of NO in placentas of each group (n = 10).  < 0.001 vs. control.  < 0.01 and  < 0.001 vs. PIH.  < 0.05 and  < 0.01 vs. MLB 5 mg/kg. MLB, magnesium lithospermate B; PIH, pregnancy-induced hypertension; VEGF, vascular endothelial growth factor; eNOS, endothelial nitric oxide synthase; NO, nitric oxide.

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