Sex Differences in the Renal Vascular Responses of AT1 and Mas Receptors in Two-Kidney-One-Clip Hypertension
Table 2
The baseline hemodynamics data.
Groups
MAP (mmHg)
RPP (mmHg)
RBF (ml/min)
RVR (mmHg·min/ml)
Male
Vehicle (n = 9)
120.4 ± 6.4
109.1 ± 10.6
2.9 ± 0.2
41.9 ± 7.5
Losartan (n = 8)
124.2 ± 3.3
115.4 ± 3.5
3.1 ± 0.3
41.2 ± 5.1
A779 (n = 7)
112.7 ± 6.6
100.1 ± 7.3
2.6 ± 0.3
41.8 ± 5.3
A779 + losartan (n = 6)
124.3 ± 6.8
114.1 ± 8.97
2.2 ± 0.3
57.3 ± 9.9
P(ANOVA)
0.51
0.60
0.22
0.39
Female
Vehicle (n = 10)
114.8 ± 6.4
105.2 ± 5.5
2.4 ± 0.3
48.5 ± 6.1
Losartan (n = 7)
116.2 ± 8.6
108.9 ± 9.3
2.3 ± 0.3
47.1 ± 5.5
A779 (n = 9)
114.5 ± 3.5
108.0 ± 3.6
2.4 ± 0.3
50.0 ± 5.5
A779 + losartan (n = 8)
113.2 ± 6.6
101.6 ± 6.6
1.8 ± 0.1
59.7 ± 5.8
(ANOVA)
0.99
0.85
0.35
0.48
MAP, RPP, RBF, and RVR stand for mean arterial pressure, renal perfusion pressure, renal blood flow, and renal vascular resistance, respectively. The data were reported as mean ± standard error of mean. The statistical values were obtained using one-way ANOVA followed by the LSD post hoc test.
