Research Article

Association between ZFHX3 and PRRX1 Polymorphisms and Atrial Fibrillation Susceptibility from Meta-Analysis

Table 3

Publication bias tests (Begg’s funnel plot and Egger’s test for the publication bias test) for ZFHX3 and PRRX1 genes’ two common polymorphisms (rs2106261 and rs3903239).

Egger’s testBegg’s test
Genetic typeCoefficientStandard errort value95%CI of interceptz value

ZFHX3 rs2106261
A-allele vs. G-allele3.3722.3131.460.205(−2.573−9.317)1.20.23
AG vs. GG2.5231.5071.670.155(−1.351−6.398)1.20.23
AA + AG vs. GG2.7441.5431.780.133(−1.223−6.712)1.20.23
AA vs. GG1.6710.9771.710.148(−0.840−4.182)1.20.23
AA vs. AG + GG1.6901.0831.560.179(−1.094−4.475)1.20.23

PRRX1 rs3903239
C-allele vs. T-allele1.0349.7710.110.933(−123.117−125.186)0.01.00
CT vs. TT0.4967.2430.070.956(−91.538−92.531)0.01.00
CC + CT vs. TT0.4717.5300.060.960(−95.213−96.154)0.01.00
CC vs. TT0.2513.8340.070.958(−48.468−48.971)0.01.00
CC vs. CT + TT0.2904.0310.070.954(−50.938−51.519)0.01.00