Hypertension is a leading modifiable risk factor for cardiovascular disease (CVD) affecting about two-thirds of the world’s population. As a complex disorder, a better understanding of the mechanisms and risk factors is of critical importance for the prevention and management of this debilitating disorder and CVD. Recently, omics studies have become more and more frequent. The advance of multiomics studies has helped uncover many potential candidate biomarkers or risk factors for hypertension and its related vascular disorders. Studies deeply exploring these biomarkers are urgent for translational medicine.

In this special issue, we plan to extensively highlight knowledge about the newly identified biomarkers, including genetic, epigenetic, and metabolic markers, for hypertension and vascular disorders, including basic, clinical, epidemiologic, and genetic findings. Here, vascular disorders include cardiovascular diseases (myocardial infarction, angina, and heart failure), stroke, and pereripheral vascular disease. Multiomics studies including genomics, epigenomics, transcriptomics, proteomics, metabolomics, and gut microbiome studies are particularly welcome.

Potential topics include but are not limited to the following:

• Epigenetic markers for hypertension and vascular disorders
• Metabolites involved in the pathogenesis of hypertension and vascular disorders
• Novel proteins and related pathways involved in hypertension and vascular disorders
• The identification of lifestyle behaviors and environmental factors that modify the genetic susceptibility of hypertension and its related disorders
• Novel findings linking early life experience to the development of hypertension and vascular disorders in later life
• Potential biomarkers linking hypertension with its complications and related diseases, such as stroke