Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling

<table>A model for the regulation of fibroblasts by KLF5 during cardiac hypertrophy. The transcription factor KLF5 controls <i>Igf1</i> and <i>Pdgfa</i> expression in cardiac fibroblasts. IGF-1 is a major cardiotrophic factor secreted from fibroblasts, and PDGF-A is primarily involved in mediating the migration and proliferation of fibroblasts.</table>

International Journal of Inflammation

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Figure 3

Figure 3: Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling 