Pharmacological Evaluation of the SCID T Cell Transfer Model of Colitis: As a Model of Crohn's Disease
Figure 4
Changes in key disease parameters following treatment. Key disease parameters (weight loss, WBC counts, and colon W : L ratio) are depicted for preventive treatment (a–c) and interventive treatment (d–f). Disease parameters are shown as ((post mortem weight−start weight)/Start weight)*100, (WBC count of drug/WBC count of control)*100, (W : L ratio of drug/W : L ratio of control)*100. (a and d) White bars represent vehicle control groups, grey bars represent treatment groups, and black bars represent mice which were not reconstituted but received treatment. (b, c, e, and f) Grey bars represent relative WBC counts and W : L ratios.