Assessment of the Microbiota in Microdissected Tissues of Crohn's Disease Patients

Table 1

Patient characteristics.

Patient	Sex	Age	Diagnosis	CARD15-SNP8	CARD15-SNP12	CARD15-SNP13	Procedure
1 (*)	♂	32	CD	WT	WT	WT	Right hemicolectomy
2 (*)	♀	36	CD	HE	WT	WT	Right hemicolectomy
3 (*)	♂	22	CD	HE	HE	WT	Right hemicolectomy
4 (*)	♂	18	CD	HO	WT	WT	Right hemicolectomy
5	♂	38	ASLC	ND	ND	ND	Colonoscopy
6 (**)	♂	70	ASLC	ND	ND	ND	Colonoscopy
7	♀	17	PMC	ND	ND	ND	Colonoscopy
8 (^§)	♂	64	PMC	ND	ND	ND	Colonoscopy
9	♀	75	DIV	ND	ND	ND	Colonoscopy
10 (^§§)	♂	48	DIV	ND	ND	ND	Colonoscopy
11 (*)	♀	65	AC	WT	WT	WT	Right hemicolectomy
12 (*)	♀	55	AC	WT	WT	WT	Total colectomy
13 (*)	♀	65	AC	HE	WT	WT	Total colectomy

ASLC: acute self-limited colitis, PMC: pseudomembranous colitis, DIV: diverticulitis, AC: adenocarcinoma.
WT: wild type, HE: heterozygous, HO: homozygous, ND: Not determined.
SNP8: Arg702Trp, SNP12: Gly908Arg, SNP13: Leu1007fsinsC.
(*) Treated with preoperative antibiotic coverage (cefazoline 2 g IV + metronidazole 1.5 g IV at induction).
(**) Treated with amoxicillin for 2 weeks prior to colonoscopy.
(^§) Clostridium difficile toxin assay positive.
(^§§) Treated with amoxicillin + clavulanic acid and levoflaxacin for 10 days prior to colonoscopy.