Renin-Angiotensin System Hyperactivation Can Induce Inflammation and Retinal Neural Dysfunction

Figure 1

Circulating and tissue renin-angiotensin system (RAS). VSMC: vascular smooth muscle cell, EC: endothelial cell, PRRB: (pro)renin receptor blockers, ACEI: angiotensin-converting enzyme inhibitors, ARB: angiotensin II type 1 receptor blockers, AT1R: angiotensin II type 1 receptor, CB: ciliary body, RPE: retinal pigment epithelium.