980327.fig.002a
(a)
980327.fig.002b
(b)
Figure 2: Effect of pharmacological inhibitors on Hp dependent IL-10 secretion. Effect of (a) colchicine (1.25–10  mol/L) and (b) Ly294002 (6.25–50  mol/L) on IL-10 release by CD163+ human monocyte-derived macrophages stimulated with polymorphic Hp:Hb complexes (1 mg/mL) for 24 h. Results are expressed as mean IL-10 (pg/mL) ± SEM from experiments.