Table of Contents Author Guidelines Submit a Manuscript
International Journal of Inflammation
Volume 2014 (2014), Article ID 896864, 5 pages
http://dx.doi.org/10.1155/2014/896864
Research Article

Clinical Feature of Intrahepatic B-Lymphocytes in Chronic Hepatitis B

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Centre, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Avenue, Tehran 14117 13135, Iran

Received 7 September 2013; Accepted 28 October 2013; Published 21 January 2014

Academic Editor: Jean-Marc Cavaillon

Copyright © 2014 Ashraf Mohamadkhani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Montazeri, “Current treatment of chronic hepatitis B,” Archives of Iranian Medicine, vol. 9, no. 1, pp. 1–10, 2006. View at Google Scholar · View at Scopus
  2. A. Mohamadkhani, M. Sotoudeh, S. Bowden et al., “Downregulation of HLA class II molecules by G1896A pre-core mutation in chronic hepatitis B virus infection,” Viral Immunology, vol. 22, no. 5, pp. 295–300, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Poustchi, A. Mohamadkhani, S. Bowden et al., “Clinical significance of precore and core promoter mutations in genotype D hepatitis B-related chronic liver disease,” Journal of Viral Hepatitis, vol. 15, no. 10, pp. 753–760, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. M. A. Aller, I. Prieto, S. Argudo et al., “The interstitial lymphatic peritoneal mesothelium axis in portal hypertensive ascites: when in danger, go back to the sea,” International Journal of Inflammation, vol. 2010, Article ID 148689, 2010. View at Publisher · View at Google Scholar
  5. A. P. Holt, E. L. Haughton, P. F. Lalor, A. Filer, C. D. Buckley, and D. H. Adams, “Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver,” Gastroenterology, vol. 136, no. 2, pp. 705–714, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Iannacone, G. Sitia, and L. G. Guidotti, “Pathogenetic and antiviral immune responses against hepatitis B virus,” Future Virology, vol. 1, pp. 189–196, 2006. View at Google Scholar
  7. B. Oliviero, A. Cerino, S. Varchetta et al., “Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections,” Journal of Hepatology, vol. 55, no. 1, pp. 53–60, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. F. Marra, S. Aleffi, S. Galastri, and A. Provenzano, “Mononuclear cells in liver fibrosis,” Seminars in Immunopathology, vol. 31, no. 3, pp. 345–358, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Farci, G. Diaz, Z. Chen et al., “B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 19, pp. 8766–8771, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Duddy, M. Niino, F. Adatia et al., “Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis,” Journal of Immunology, vol. 178, no. 10, pp. 6092–6099, 2007. View at Google Scholar · View at Scopus
  11. S. Tayebi and A. Mohamadkhani, “The TNF-alpha-308 promoter gene polymorphism and chronic HBV infection,” Hepatitis Research and Treatment, vol. 2012, Article ID 493219, 2012. View at Google Scholar
  12. R. Avila-Flores and R. A. Medellín, “Ecological, taxonomic, and physiological correlates of cave use by Mexican bats,” Journal of Mammalogy, vol. 85, no. 4, pp. 675–687, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. D. J. Decker, P.-J. Linton, S. Zaharevitz, M. Biery, T. R. Gingeras, and N. R. Klinman, “Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro,” Immunity, vol. 2, no. 2, pp. 195–203, 1995. View at Google Scholar · View at Scopus
  14. M. S. Cragg, C. A. Walshe, A. O. Ivanov, and M. J. Glennie, “The biology of CD20 and its potential as a target for mAb therapy,” Current directions in autoimmunity, vol. 8, pp. 140–174, 2005. View at Google Scholar · View at Scopus
  15. K. Ishaka, A. Baptistab, L. Bianchic, F. Callead, J. D. Grootee, and F. Gudatf, “Histological grading and staging of chronic hepatitis,” Journal of Hepatology, vol. 22, pp. 696–699, 1995. View at Google Scholar
  16. R. K. Bhogal and C. A. Bona, “B cells: no longer bystanders in liver fibrosis,” Journal of Clinical Investigation, vol. 115, no. 11, pp. 2962–2965, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Mohamadkhani, F. Bastani, M. Sotoudeh et al., “Influence of B cells in liver fibrosis associated with hepatitis B virus harboring basal core promoter mutations,” Journal of Medical Virology, vol. 84, pp. 1889–1896, 2012. View at Google Scholar
  18. A. P. Holt, Z. Stamataki, and D. H. Adams, “Attenuated liver fibrosis in the absence of B cells,” Hepatology, vol. 43, no. 4, pp. 868–871, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. T. I. Novobrantseva, G. R. Majeau, A. Amatucci et al., “Attenuated liver fibrosis in the absence of B cells,” Journal of Clinical Investigation, vol. 115, no. 11, pp. 3072–3082, 2005. View at Publisher · View at Google Scholar · View at Scopus