Role of MicroRNAs in Renin-Angiotensin-Aldosterone System-Mediated Cardiovascular Inflammation and Remodeling

Table 1

MicroRNAs affected by RAAS effectors.

Effector	MicroRNA target gene	Reference
Angiotensin II
miR-155	ATR1, eNOS, α-SMA, NF-κB, AP-1	[11–14, 16, 48]
↓ miR-29-b	TGFbeta, Col 1A, α-SMA	[18, 24, 33–35]
↓ miR-483-3p	AGT, ACE-1, ACE-2, AT2R	[29]
↓ miR-129-3p	FAK, MMP-2, MMP-9	[23]
↑ miR-132/212	AT1R, MSK, Gαβ/ERK1/2	[19, 21]
↓ miR-34	ANP, β-MHC	[46, 49]
miR-766	Cyp11B2	[25]
miR-16	Ang II, CCDN1, CCDN2, CCDNE	[47]

Note: ↓: decreased expression level; ↑: increased expression level.