Smoking Status Effect on Inflammatory Markers in a Randomized Trial of Current and Former Heavy Smokers

Table 4

Stepwise regression analysis for CRP and IL-6 by smoking status.

Subjects	Explanatory variable			Adjusted
CRP (mg/L)
Former smokers	Total triglycerides	0.496	0.009	0.455
	CRP IL-6	<0.001	0.000
Smokers	HDL-C (mg/dL)	−0.017	0.010	0.369
	BMI (kg/m^2)	0.028	0.052
	CRP IL-6	<0.001	0.000
IL-6 (pg/mL)
Former smokers	Total triglycerides	0.442	0.002	0.547
	Age	0.027	0.007
	CRP IL-6	<0.001	0.000
Smokers	Pack/year	0.012	0.005	0.436
	CRP IL-6	<0.001	0.000

CRP: C-reactive protein; IL-6: interleukin 6; HDL-C: high density lipoprotein; BMI: body mass index, and CRP IL-6: interaction between CRP and IL-6.
Variables included in the model are gender, age, BMI, total triglycerides, HDL-C, years of smoking, pack/year, caloric intake/day, and interaction between CRP and IL-6.