Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of Sonapatha Oroxylum indicum In Vivo

Table 3

Alteration in the response time in mice treated with Oroxylum indicum before subjecting them to tail immersion test.

Treatment	Dose (mg/kg b.wt.)	Response time in seconds ± SEM
		Assessment time (h)
		0	0.5	1	2	3	4	5	6
Control	0	4.30 ± 0.05	4.2 ± 0.20	4.03 ± 0.12	4.6 ± 0.35	4.81 ± 0.51	4.62 ± 0.42	4.31 ± 0.37	4.30 ± 0.40
OIE	300	5.67 ± 0.20	6.33 ± 0.15	6.78 ± 0.51	8.80 ± 0.06	7.56 ± 0.05	6.98 ± 0.15	6.80 ± 0.20	6.61 ± 0.27
			(11.64)	(19.57)	(55.20)	(33.33)	(23.10)	(19.92)	(16.57)
	250	4.69 ± 0.50	4.72 ± 0.08	4.97 ± 0.30	4.78 ± 0.46	7.14 ± 0.54	5.65 ± 0.65	4.90 ± 0.15	4.80 ± 0.10
			(1.91)	(5.97)	(19.18)	(52.23)	(20.46)	(4.47)	(2.35)
Diclofenac	20	4.29 ± 0.08	4.43 ± 0.20	5.03 ± 0.11	6.76 ± 0.5	7.31 ± 0.57	6.87 ± 0.48	6.39 ± 0.47	4.50 ± 0.70
			(3.26)	(17.29)	(57.57)	(70.39)	(60.13)	(48.95)	(4.89)

Inhibition (%) is shown in brackets.
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when compared to SPS treated control.