Osteoarthritis Affects Mammalian Oogenesis: Effects of Collagenase-Induced Osteoarthritis on Oocyte Cytoskeleton in a Mouse Model

Figure 2

Meiotic spindle width. (a, b) Data for M I and (c, d) data for M II. (a) M I mean spindle width (total mean ± 1 SD), comparison of controls (11.64 ± 2.51 μm, n = 86) and CIOA (18.04 ± 4.05 μm, n = 116); independent samples t-test, . (b) Distribution of M I spindle width category frequencies in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 86): slender (n = 9), normal (11.64 ± 2.51 μm, n = 67), and wide (n = 10); CIOA (n = 139): slender (n = 1), normal (11.64 ± 2.51 μm, n = 43), and wide (n = 95); Fisher–Freeman–Halton Exact Test, . (c) M II mean spindle width (total mean ± 1 SD), comparison of controls (12.64 ± 2.68 μm, n = 116), and CIOA (17.34 ± 3.99 μm, n = 51); independent samples t-test, . (d) Distribution of M II spindle width category frequencies in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 116): slender (n = 10), normal (12.64 ± 2.68 μm, n = 97), and wide (n = 9); CIOA (n = 51): normal (12.64 ± 2.68 μm, n = 23) and wide (n = 28); Fisher–Freeman–Halton Exact Test, .

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