Impact of Vitamin C on Gene Expression Profile of Inflammatory and Anti-Inflammatory Cytokines in the Male Partners of Couples with Recurrent Pregnancy Loss

Table 2

Comparison of relative cytokines genes expression before and after treatment with vitamin C.

Genes	Before treatment (N = 20)	After treatment (N = 20)	value
IL-10	0.95 ± 0.21	0.49 ± 0.08	0.13
IL-4	0.016 ± 0.016	0.28 ± 0.08	0.01
TGF-β	0.03 ± 0.02	0.63 ± 0.31	0.02
IL-6	2.01 ± 0.39	1.16 ± 0.04	<0.001
TNF-⍺	0.16 ± 0.15	0.11 ± 0.04	0.007
IFN-γ	0.48 ± 0.25	2.21 ± 0.38	0.002

Data are presented as the mean ± SEM according to the Wilcoxon test. was considered as a significant value. IL-10, interleukin 10; IL-4, interleukin 4;TGF-β, transforming growth factor-beta; IL-6, interleukin 6; TNF-⍺, tumor necrosis factor-alpha; IFN-γ, interferon-gamma.