Cytotoxic Activity and Lymphocyte Subtypes in Mice Selected for Maximal and Minimal Inflammatory Response after Transplantation of B16F10 and S91 Melanoma Cells

Figure 1

Cytotoxic activity of effector nonadherent spleen cells of acute inflammatory response (AIR) mice (n = 6) using lactate dehydrogenase activity released into the supernatant from the cytosol of damaged cells. The results are expressed as a mean percentage and standard deviation of specific lysis against the Yac.1 target cells (effector to target cell ratio 10:1). Lowercase letters indicate comparison of cytotoxic activity within the same AIR mouse line (a > b,  < 0.05); capital letters indicate a comparison of cytotoxic activity between AIRmax and AIRmin (A > B,  < 0.05).