International Journal of Inflammation

Curbing Inflammation


Publishing date
27 Sep 2013
Status
Published
Submission deadline
10 May 2013

1Edmund Cohen Laboratory for Vascular Research, The University of The West Indies, Bridgetown, Barbados

2Rheumatology Research Group, School of Immunity and Infection, University of Birmingham, Birmingham, UK

3Laboratory of Cardiovascular and Endothelial Function, Department of Surgery and Anatomy, School of Medicine of Ribeirão Preto, University of Sao Paulo, Sao Paulo, SP, Brazil

4MCCAIG Institute for Bone and Joint Health, University of Calgary, Calgary, AB, Canada


Curbing Inflammation

Description

Inflammation stands at the centre of a range of natural and pathological processes, such as ageing, wound healing, infection, arthritis, autoimmune disease, cardiovascular disease, cancer, and the inflammatory response to trauma or surgery. It is well accepted that inflammation, in the right place and at the right time, is at the center of a healthy host response to natural or man-made stresses. However, systemic or runaway inflammation is pathological and it is incumbent to understand better how the inflammatory process is curbed, either naturally or with intervention. We invite authors to submit original research articles as well review articles on strategies to curb inflammation in the following three areas (priority will be given to studies underpinned with plausible mechanisms of action):

  • Spontaneous resolution
    • Much can be learnt from self-resolving arthritides and other relapsing/remitting syndromes (e.g., gout, spondyloarthritis, and autoinflammatory syndromes), for which detailed anti-inflammatory pathways have been described. Such pathways are exemplified but not limited to:
      • Anti-inflammatory cytokines (e.g., IL-10, transforming growth factor (TGF) beta)
      • Acute phase proteins (e.g., alpha 1 antitrypsin, hemopexin, haptoglobin, and adiponectin)
      • Glucocorticoids (e.g., cortisol)
      • Neuromediators (e.g., norepinephrine, acetylcholine)
      • Lipid mediators (e.g., lipoxin, resolvin, and maresin)
  • Resolution in the context of chronic inflammation
    • Curbing inflammation can be a challenge in the setting of chronic inflammation or nonhealing wounds. Treatment approaches are invited in the context of:
      • Arthritis
      • Autoimmune conditions
      • Inflammatory bowel disease
      • Nonhealing wounds (e.g., diabetes)
  • Attenuating the systemic inflammatory response
    • A systemic inflammatory response may arise in critical care heart surgery patients. Priority targets:
      • Anti-inflammatory treatments for the systemic inflammatory response syndrome (SIRS) in trauma victims (e.g., burns, hemorrhage, and ischemia-reperfusion injury)
      • Pharmacological or circuit modifications strategies to attenuate the systemic inflammatory response to heart surgery
      • Predisposing factors (e.g., genetic or comorbid factors) that place patients at increased risk of systemic inflammation

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/iji/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/iji/curb/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 468287
  • - Editorial

Curbing Inflammation

R. Clive Landis | Christopher D. Buckley | ... | David A. Hart
  • Special Issue
  • - Volume 2013
  • - Article ID 434586
  • - Research Article

Statin Modulation of Human T-Cell Proliferation, IL-1 and IL-17 Production, and IFN- T Cell Expression: Synergy with Conventional Immunosuppressive Agents

Ashmal Jameel | Kenneth G.-J. Ooi | ... | Virginia L. Calder
  • Special Issue
  • - Volume 2013
  • - Article ID 781024
  • - Research Article

Preoperative White Blood Cell Count and Risk of 30-Day Readmission after Cardiac Surgery

Jeremiah R. Brown | R. Clive Landis | ... | Anthony W. DiScipio
  • Special Issue
  • - Volume 2013
  • - Article ID 601424
  • - Review Article

Metabolic Acidosis Treatment as Part of a Strategy to Curb Inflammation

Tales Rubens de Nadai | Mariane Nunes de Nadai | ... | Paulo Roberto Barbosa Evora
  • Special Issue
  • - Volume 2013
  • - Article ID 183061
  • - Review Article

Curbing Inflammation in the Ischemic Heart Disease

Paulo Roberto B. Evora | Julio Nather | ... | Alfredo J. Rodrigues
  • Special Issue
  • - Volume 2013
  • - Article ID 578480
  • - Review Article

Blocking Neurogenic Inflammation for the Treatment of Acute Disorders of the Central Nervous System

Kate Marie Lewis | Renée Jade Turner | Robert Vink
  • Special Issue
  • - Volume 2013
  • - Article ID 715645
  • - Review Article

Curbing Inflammation in Burn Patients

Jayme A. Farina | Marina Junqueira Rosique | Rodrigo G. Rosique
  • Special Issue
  • - Volume 2013
  • - Article ID 985815
  • - Review Article

Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides

Tazeen J. Ahmed | Trinidad Montero-Melendez | ... | Costantino Pitzalis
  • Special Issue
  • - Volume 2013
  • - Article ID 780502
  • - Research Article

Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation

Betsy J. Evans | Dorian O. Haskard | ... | R. Clive Landis
  • Special Issue
  • - Volume 2013
  • - Article ID 980327
  • - Research Article

Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages

R. Clive Landis | Pandelis Philippidis | ... | Dorian O. Haskard
International Journal of Inflammation
 Journal metrics
Acceptance rate13%
Submission to final decision64 days
Acceptance to publication36 days
CiteScore5.500
Impact Factor-
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