Table of Contents
Research Letters in Inorganic Chemistry
Volume 2008, Article ID 350921, 4 pages
Research Letter

Nickel(II) Complexes of Hydrazone of Isoniazid and Their Magneto-Spectral, Electrochemical, Thermal and Antimicrobial Investigations

1School of Chemical Sciences, Faculty of Science and Technology, The University of the South Pacific, Private Mail Bag, Laucala Campus, Suva, Fiji
2Department of Chemistry, Lajpat Rai Postgraduate College, Sahibabad, Ghaziabad 201005, India

Received 15 July 2008; Accepted 13 August 2008

Academic Editor: Tai Lau

Copyright © 2008 Surendra Prasad and Ram K. Agarwal. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The synthesis of novel nickel(II) complexes with new ligand derived from hydrazone of isoniazid has been reported. The complexes have general compositions [Ni(L)2X2] or [Ni(L)3](ClO4)2, where L = N-isonicotinamido-furfuraldimine (INH-FFL) and X=Cl or NCS. The ligand hydrazone behaves as neutral bidentate (N and O donor) through the carbonyl oxygen and azomethine nitrogen. On the basis of elemental analysis, molecular weight determinations, magnetic susceptibility/moment, thermogravimetric, electrochemical, and spectroscopic studies, the new complexes have been characterized with octahedral geometry. The antibacterial and antifungal studies of the present complexes show that they are moderate antibacterial and antifungal agents.