Research Article

Reaction of the Anticancer Organometallic Ruthenium Compound, [(-Cymene)Ru(ATSC)Cl] with Human Serum Albumin

Table 1

Binding constants for the interaction of [(cymene)Ru(ATSC)Cl] with the HSA.

Modified Stern-VolmerScatchardLineweaver-Burk
TemperatureK (104 M-1)R 2K (104 M-1)R 2K (104 M-1)R 2
(K)(f)(n)

2939.09 ± 0.48 (1.32)0.99311.5 ± 0.3 (1.22)0.9979.15 ± 0.490.993
29812.1 ± 0.3 (1.15)0.99712.7 ± 0.5 (1.13)0.99012.2 ± 0.40.997
30813.1 ± 0.8 (1.33)0.99214.7 ± 1.8 (1.27)0.98813.3 ± 1.10.982