Research Article

Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells

Table 4

Effect of the i.p administration of the purified fraction of Curcuma zedoaria on the life span of DLA tumour bearing mice.

TreatmentsNo: of mice survived after tumour inoculation (days)Mean survival time (MST) (days)Increase in life span (%)
152535

Group 1 (DLA Control)6/60/60/6
Group 2 CZPF 62.5 mg/kg bw6/63/60/6 19.0
Group 3 CZPF 50 mg/kg bw6/64/60/6 23.8
Group 4 CZPF 41.6 mg/kg bw6/64/60/6 38.0
Group 5 CZPF 35.7 mg/kg bw6/65/60/6 42.8
Group 6 CYP (25 mg/kg bw)6/66/63/6 52.3