International Journal of Medicinal Chemistry / 2011 / Article / Sch 1

Research Article

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors

Scheme 1

Synthesis of 1,3-disubstrituted tetrahydro-β-carbolines and tetrahydro-β-carboline hydantoin derived from D-tryptophan.

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