Research Article

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N-Diethyl-Substituted Amido Moieties

Table 2

Result of MIC test of α-tolylsulfonamide on targeted organisms ( g/mL).

Compd. no.Minimum inhibitory concentration ( g/mL)
Organisms
E. coli ATCC 25922 S. aureus ATCC 6538
at 100  g/mLat 1000  g/mLat 100  g/mLat 1000  g/mL

1100<1000>100250
2>1001251.8<1000
3>100>100250
4>100125>100125
5>10012550<1000
625<1000100<1000
725<1000>100500
8>100250100<1000
9>100250>100250
10>100125>100125
11100<1000>100125
1250<1000>100125
13>100250>100250
1450<100062.5<1000
15>100250>1001000
16>100>100
17>10012525<1000
18>100500>1001000
19>100250>100125
20>100125>100250
21>10025025<1000
2212.5<100025<1000
Str.6.25<1000>100125

>100 means that if there was no growth inhibition at 100  g/mL, it was repeated at 1000  g/mL, <1000  g/mL means that growth inhibition has already been experienced at lower concentration less than or equal to 100  g/mL; hence, there is no need to repeat the test at 1000  g/mL. — means no activity was observed even at 1000  g/mL. Str. means streptomycin clinical reference.