Table 1: 2-Oxo-3-phenylimidazolidine-1-carboxamide kinase inhibitors based on different scaffolds.

412614.tab.001a
CpdArc-Meta
IC50 (μM)
VEGFR2a
IC50 (μM)
TrkAa
% inh. at 0.1 μM

1412614.tab.001b0.020.0182
2412614.tab.001c0.030.0194
3412614.tab.001d0.050.1516
4412614.tab.001e0.030.2349
5412614.tab.001f0.312.5098

aIC50 and percentage of inhibition values are reported as the average of ≥3 experiments.