A DFT and Semiempirical Model-Based Study of Opioid Receptor Affinity and Selectivity in a Group of Molecules with a Morphine Structural Core

Table 5

Beta coefficients and 𝑡-test for significance of coefficients in (18).

Variable	Beta coefficient	𝑡	P
𝑄^max15	0.73	13.19	<0.000001
𝜂5	0.51	10.56	<0.000001
𝐹11(LUMO)	−0.54	−10.06	<0.000001
𝜔13	0.29	4.65	<0.0007