International Journal of Medicinal Chemistry / 2012 / Article / Tab 2

Research Article

Syntheses and In Vitro Biological Activity of Some Derivatives of C-9154 Antibiotic

Table 2

Zones of inhibition (mm) of the analogue and derivatives.

IA/12/1
(10 μg/mL)
IA/27/1/B
(5 μg/mL)
IA/28/1/B
(5 μg/mL)
IA/29/1/B
(5 μg/mL)
IA/30/1/B
(5 μg/mL)
IA/31/1/B
(5 μg/mL)
IA/32/1/B
(5 μg/mL)
DMSOSparfloxacin
(20 μg/mL)
fluconazole
(50 μg/mL)

MRSA273233303031310220
S. aureus 263029323230310270
S. pyogenes 21313202730300240
B. subtilis 333738343431290300
C. ulcerans 24030323000000
E. coli 272729262426240270
P. mirabilis 272427252724250220
P. aeruginosa 00000000200
S. typhii 292726272427270210
S. dysenteriae 312926222724250270
K. pneumoniae 302725262426250250
C. albicans 262223202022210024
A. nigre 21000000000
T. rubrum 00000000020

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