Figure 3: Androstene hormone activation of the human estrogen receptor beta. Reporter cells were treated with androstene hormones , incubated for 24 hours, and then assayed for luciferase activity. Androstene hormone activity was normalized to cellular uptake (Section 2.3.1). Error bars, ±1 SD. Statistical significance, (¤) versus androstene hormone metabolites in the same treatment group, ( ) versus lower reacting androstene hormones in the same treatment group.