Experimental Design-Based Response Surface Methodology Optimization for Synthesis of β-Mercapto Carbonyl Derivatives as Antimycobacterial Drugs Catalyzed by Calcium Pyrophosphate

Table 1

Study field and coded factors.

Natural variable	Unit	Coded variables 𝑋1, 𝑋2, and 𝑋3
		−1	0	+1
Catalyst weight	mg	40	120	200
Reaction time	min	20	30	40
Solvent volume	mL	1	2	3