Synthesis and Biological Evaluation of Aminonaphthols Incorporated Indole Derivatives

Table 3

In vitro antimicrobial activities of compounds (4a–4r).

Compound code	Antibacterial activity (MIC g/mL)				Antifungal activity (MIC g/mL)
	EC^a	SA^b	KP^c	PA^d	AO^e	AN^f	AF^g	AT^h
4a	512	1024	512	1024	512	256	256	256
4b	64	32	64	128	128	128	32	64
4c	128	128	256	128	256	128	128	256
4d	256	512	1024	512	1024	512	256	256
4e	64	64	128	64	64	128	64	128
4f	128	512	256	256	128	256	128	256
4g	1024	256	512	512	256	256	256	256
4h	16	16	64	64	16	16	64	64
4i	256	128	256	256	128	256	128	256
4j	512	1024	512	512	256	512	512	512
4k	16	16	32	32	16	16	64	32
4l	256	256	128	128	256	256	256	256
4m	512	512	512	1024	512	256	256	512
4n	16	16	08	16	08	08	16	08
4o	128	128	64	128	128	64	128	128
4p	256	256	256	512	128	128	256	256
4q	16	08	16	08	32	08	16	16
4r	64	32	64	32	32	32	32	32
Gentamycin	02	02	02	02	—	—	—	—
Fluconazole	—	—	—	—	02	02	02	02

EC: Escherichia coli (MTCC-723), ^bSA: Staphylococcus aureus (ATCC-29513), ^cKP: Klebsiella pneumonia (NCTC-13368), ^dPA: Pseudomonas aeruginosa (MTCC-1688), ^eAO: Aspergillus oryzae (MTCC-3567^T), ^fAN: Aspergillus niger (MTCC-281), ^gAF: Aspergillus flavus (MTCC-1973), and ^hAT: Aspergillus terreus (MTCC-1782).