Docking Studies and Biological Activity of Fosinopril Analogs

Table 3

Percent ACE inhibition by A3, A4, A5, and A6 at different concentrations.

Analog	Percent inhibition
	0.2 nM	0.4 nM	0.6 nM	0.8 nM	1 nM
A3	43.75 ± 3.05	56.26 ± 5.43	62.50 ± 5.11	65.62 ± 3.96	71.87 ± 4.50
A4	41.41 ± 4.88	60.05 ± 5.24	64.27 ± 3.25	65.70 ± 3.89	68.53 ± 3.67
A5	45.29 ± 3.65	52.30 ± 4.91	54.05 ± 3.79	56.77 ± 4.14	59.43 ± 5.02
A6	37.80 ± 4.76	43.29 ± 3.15	48.64 ± 4.20	51.35 ± 4.73	54.03 ± 3.99