Nitro Derivatives of Naturally Occurring β-Asarone and Their Anticancer Activity

Table 1

Cytotoxic activity for nitro derivatives of -asarone by MTT assay.

IC50 values (μM)^a
Compounds	HeLa^b	MCF-7^c	SW-982^d	PC-3^e	IMR-32^f
1
2
-Asarone		>150		>150	>150
Camptothecin

IC₅₀: each set of data represents mean ± S.D from three different test results in triplicate and is expressed as the concentration of test compound which inhibits the cell growth by 50%.
^bHeLa: human cervical cancer; ^cMCF-7: human breast cancer; ^dSW-982: human synovial sarcoma; ^ePC-3: human prostate cancer; ^fIMR-132: human neuroblastoma.