Clicked Cinnamic/Caffeic Esters and Amides as Radical Scavengers and 5-Lipoxygenase Inhibitors

Table 2

Determination of IC₅₀ values of selected inhibitors.

Compound	HEK293; IC50 (μM) [SD]	Human PMNL; IC50 (μM) [SD]
1	8.4 [1.4]	2.7 [0.4]
15f	2.1 [0.3]	3.1 [0.2]
15g	1.6 [0.2]	3.3 [0.2]
16f	5.9 [1.3]	8.2 [0.8]
16g	7.6 [1.4]	8.8 [0.7]