International Journal of Medicinal Chemistry

Research Article

Synthesis and Biological Activity of Arylspiroborate Salts Derived from Caffeic Acid Phenethyl Ester

Table 3

5-LO inhibition in PMNL cells.
CompoundsIC50 (M) [SEM]
Zileuton3.20 0.3
CAPE (3)1.11 0.03
40.60 0.05
50.84 0.03
Two independent experiments, each performed in duplicate.