Review Article

A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model

Figure 31

The two-dimensional representation of the Milwaukee-based unified pharmacophore with 3 amino acids in the binding site based on the rigid ligand template [23, 39, 42, 76ā€“80]. This figure has been modified from that reported for PAMs, NAMs, and antagonists in [22, 23].