Fluorinated Adenosine A_2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics

Figure 2

ConA-induced liver damage in C57BL/6 mice via CGS (6), 2, 3 and 4. Female C57BL/6 mice () were first injected with R agonist CGS (6, 2 mg kg⁻¹), 2 mg kg⁻¹ 2, 3, and 4 separately, and then Con A (20 mg kg⁻¹). Con A-induced liver damage evaluated at 8 h.