Effect of Peptide Receptor Radionuclide Therapy on Somatostatin Receptor Status and Glucose Metabolism in Neuroendocrine Tumors: Intraindividual Comparison of Ga-68 DOTANOC PET/CT and F-18 FDG PET/CT
Table 3
Different response patterns according to tumor location.
Location
Group
PET/CT
Before PRRT
After PRRT
N
SUVmax
N
SUVmax
Primary sites
Mat
SMS
10
23.2 ± 11.0
9
17.6 ± 8.0*
FDG
10
9.0 ± 4.2
9
8.2 ± 4.2
Mis
SMS
9
14.5 ± 13.5
5
12.9 ± 14.7
LN
Mat
SMS
17
21.3 ± 13.6
17
15.3 ± 9.6†
FDG
17
9.5 ± 5.1
16
8.4 ± 5.3
Mis
SMS
9
10.5 ± 5.1
5
7.5± 7.4
Liver
Mat
SMS
42
26.5 ± 13.9
39
19.6 ± 9.5†
FDG
42
8.8 ± 4.2
32
6.2 ± 3.6†
Mis
SMS
22
19.0 ± 7.4
21
14.9 ± 5.7*
FDG
7
12.6 ± 5.0
7
16.9 ± 8.0*
Bone
Mat
SMS
9
9.9 ± 3.5
9
9.6 ± 4.9
FDG
9
8.6 ± 3.2
7
3.2 ± 1.6*
Mis
SMS
8
7.5 ± 3.1
7
5.1 ± 3.1*
Abbreviations: Mat: matched, Mis: mismatched, LN: lymph nodes. †: P < 0.0001, *: P < 0.05.