Research Article

Effect of Peptide Receptor Radionuclide Therapy on Somatostatin Receptor Status and Glucose Metabolism in Neuroendocrine Tumors: Intraindividual Comparison of Ga-68 DOTANOC PET/CT and F-18 FDG PET/CT

Table 3

Different response patterns according to tumor location.

LocationGroupPET/CTBefore PRRTAfter PRRT
NSUVmaxNSUVmax

Primary sitesMatSMS1023.2 ± 11.0917.6 ± 8.0*
FDG109.0 ± 4.298.2 ± 4.2
MisSMS914.5 ± 13.5512.9 ± 14.7

LNMatSMS1721.3 ± 13.61715.3 ± 9.6
FDG179.5 ± 5.1168.4 ± 5.3
MisSMS910.5 ± 5.157.5± 7.4

LiverMatSMS4226.5 ± 13.93919.6 ± 9.5
FDG428.8 ± 4.2326.2 ± 3.6
MisSMS2219.0 ± 7.42114.9 ± 5.7*
FDG712.6 ± 5.0716.9 ± 8.0*

BoneMatSMS99.9 ± 3.599.6 ± 4.9
FDG98.6 ± 3.273.2 ± 1.6*
MisSMS87.5 ± 3.175.1 ± 3.1*

Abbreviations: Mat: matched, Mis: mismatched, LN: lymph nodes.
: P < 0.0001, *: P < 0.05.