Table of Contents
International Journal of Molecular Imaging
Volume 2011 (2011), Article ID 630813, 6 pages
Research Article

Reduction of Collimator Correction Artefacts with Bayesian Reconstruction in Spect

1Department of Radiation Therapy, Vaasa Central Hospital, Hietalahdenkatu 2-4, 65100 Vaasa, Finland
2HERMES Medical Solutions, Skeppsbron 44, 11130 Stockholm, Sweden
3Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, P.O. Box 1777, 70211 Kuopio, Finland
4Niuvanniemi Hospital, 70211 Kuopio, Finland

Received 30 July 2010; Revised 29 September 2010; Accepted 29 October 2010

Academic Editor: Thomas Beyer

Copyright © 2011 Tuija Kangasmaa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Poor resolution of single photon emission computed tomography (SPECT) has degraded its use in clinical practice. Collimator correction has been shown to improve the reconstructed resolution, but the correction can generate ringing artefacts, which lower image quality. This paper investigates whether Bayesian reconstruction methods could reduce these artefacts. We have applied and tested three Bayesian reconstruction methods: smoothing prior, median root prior, and anatomical prior. To demonstrate the efficacy of these methods, we compared their physical and visual performance both in phantom and patient studies. All the three Bayesian reconstruction methods reduced the collimator correction artefacts. Images reconstructed using the smoothing prior and the median root prior had slightly lower contrast than the standard reconstruction with collimator correction, whereas the anatomical prior produced images with good resolution and contrast.