Table of Contents
International Journal of Molecular Imaging
Volume 2011 (2011), Article ID 782758, 4 pages
http://dx.doi.org/10.1155/2011/782758
Case Report

Alleviation of Brain Hypoperfusion after Preventative Treatment with Lomerizine in an Elderly Migraineur with Aura

1Department of Neurology, Mishuku Hospital, 5-33-12 Kamimeguro, Meguroku, Tokyo 153-0051, Japan
2Department of Neurology, Toho University Omori Medical Center, 6-11-1 Omorinishi, Otaku, Tokyo 143-8541, Japan

Received 19 July 2010; Accepted 6 December 2010

Academic Editor: Ronald L. Van Heertum

Copyright © 2011 Joe Aoyagi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Olesen, B. Larsen, and M. Lauritzen, “Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine,” Annals of Neurology, vol. 9, no. 4, pp. 344–352, 1981. View at Google Scholar · View at Scopus
  2. M. Lauritzen and J. Olesen, “Regional cerebral blood flow during migraine attacks by Xenon-133 inhalation and emission tomography,” Brain, vol. 107, no. 2, pp. 447–461, 1984. View at Google Scholar · View at Scopus
  3. J. Olesen, L. Friberg, T. S. Olsen et al., “Timing and topography of cerebral blood flow, aura, and headache during migraine attacks,” Annals of Neurology, vol. 28, no. 6, pp. 791–798, 1990. View at Publisher · View at Google Scholar · View at Scopus
  4. E. Merckx, C. Schiepers, A. Verbruggen, J. Janssens, and M. De Roo, “Brain perfusion scintigraphy with 99mTc ethylcysteinate dimer for migraine accompagnee,” Clinical Nuclear Medicine, vol. 19, no. 10, pp. 922–923, 1994. View at Google Scholar · View at Scopus
  5. H. Seto, M. Shimizu, R. Futatsuya et al., “Basilar artery migraine reversible ischemia demonstrated by Tc-99m HMPAO brain SPECT,” Clinical Nuclear Medicine, vol. 19, no. 3, pp. 215–218, 1994. View at Google Scholar · View at Scopus
  6. M. D. Ferrari, J. Haan, J. A. K. Blokland et al., “Cerebral blood flow during migraine attacks without aura and effect of sumatriptan,” Archives of Neurology, vol. 52, no. 2, pp. 135–139, 1995. View at Google Scholar · View at Scopus
  7. S. Soriani, L. Feggi, P. A. Battistella, C. Arnaldi, L. De Carlo, and S. Stipa, “Interictal and ictal phase study with Tc 99m HMPAO brain SPECT in juvenile migraine with aura,” Headache, vol. 37, no. 1, pp. 31–36, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. I. La Spina, A. Vignati, and D. Porazzi, “Basilar artery migraine: transcranial doppler EEG and SPECT from the aura phase to the end,” Headache, vol. 37, no. 1, pp. 43–47, 1997. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Iwamoto, T. Morita, T. Kanazawa, H. Ohtaka, and K. Ito, “Effects of KB-2697, a new calcium antagonist, and other diphenylpiperazines on [3H]nitrendipine binding,” Japanese Journal of Pharmacology, vol. 48, no. 2, pp. 241–247, 1988. View at Google Scholar · View at Scopus
  10. F. Gotoh, K. Tashiro, N. Kutsuzawa et al., “Clinical evaluation of KB-2796 (lomerizine hydrochloride) on migraine: late phase II study,” Clinical Evaluation, vol. 23, pp. 13–37, 1995 (Japanese). View at Google Scholar
  11. F. Gotoh, Y. Fukuuchi, K. Tashiro et al., “Clinical evaluation of lomerizine on migraine: double-blind study in comparison with demetotiazine,” Clinical Evaluation, vol. 23, pp. 183–214, 1995 (Japanese). View at Google Scholar
  12. F. Gotoh, Y. Fukuuchi, K. Tashiro et al., “Long-term trial of lomerizine hydrochloride for migraine,” Japanese Pharmacology and Therapeutics, vol. 23, pp. 1445–1460, 1995 (Japanese). View at Google Scholar
  13. N. Imai, T. Konishi, M. Serizawa, and T. Okabe, “Do the effects of long-term lomerizine administration differ with age?” Internal Medicine, vol. 46, no. 10, pp. 683–684, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. R. Takeuchi, Y. Yonekura, H. Matsuda, and J. Konishi, “Usefulness of a three-dimensional stereotaxic ROI template on anatomically standardised 99mTc-ECD SPET,” European Journal of Nuclear Medicine, vol. 29, no. 3, pp. 331–341, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Matsuda, A. Yagishita, S. Tsuji, and K. Hisada, “A quantitative approach to technetium-99m ethyl cysteinate dimer: a comparison with technetium-99m hexamethylpropylene amine oxime,” European Journal of Nuclear Medicine, vol. 22, no. 7, pp. 633–637, 1995. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Köseoglu, A. Talaslioglu, A. S. Gönül, and M. Kula, “The effects of magnesium prophylaxis in migraine without aura,” Magnesium Research, vol. 21, no. 2, pp. 101–108, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Shimazawa, H. Hara, T. Watano, and T. Sukamoto, “Effects of Ca channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats,” British Journal of Pharmacology, vol. 115, no. 8, pp. 1359–1368, 1995. View at Google Scholar · View at Scopus
  18. H. Hara, M. Shimazawa, M. Sasaoka et al., “Selective effects of lomerizine, a novel diphenylmethylpiperazine Ca2+ channel blocker, on cerebral blood flow in rats and dogs,” Clinical and Experimental Pharmacology and Physiology, vol. 26, no. 11, pp. 870–876, 1999. View at Publisher · View at Google Scholar
  19. M. Ishii, S. Kobayashi, M. Ohkura, R. Yamamoto, S. Shimizu, and Y. Kiuchi, “Inhibitory effect of lomerizine, a prophylactic drug for migraines, on serotonin-induced contraction of the basilar artery,” Journal of Pharmacological Sciences, vol. 111, no. 2, pp. 221–225, 2009. View at Publisher · View at Google Scholar
  20. M. Selt, C. A. Bartlett, A. R. Harvey, S. A. Dunlop, and M. Fitzgerald, “Limited restoration of visual function after partial optic nerve injury; a time course study using the calcium channel blocker lomerizine,” Brain Research Bulletin, vol. 81, no. 4-5, pp. 467–471, 2010. View at Publisher · View at Google Scholar