Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and Integrin
Figure 5
Immunofluorescence histochemistry of the sections from the aortic arch apoEā/ā mice on a high cholesterol diet. (a) IntegriSense, (b) ProSense, red: imaging agent, green: CD 68 antibody staining monocytes/macrophages, blue: DAPI staining of cell nucleus, yellow arrows: colocalization of agents and macrophages, red arrows: distribution of agents in the core of atherosclerotic lesion, Adv: adventitia.