Region-Based Partial Volume Correction Techniques for PET Imaging: Sinogram Implementation and Robustness
Figure 1
High resolution CT (or MR) image of a vessel is segmented to create two VOI masks (a). These VOI masks are then interpolated to the coarser PET voxel size to account for the tissue fraction effect (b). Note that, unlike VOI masks in (a), voxel values in (b) may have values between zero and one in the boundary region. The PET-space VOI image is then forward projected using the 3D PET scanner geometry (c). The projection image is blurred in sinogram-space (d). The sinograms are then reconstructed with a 3D PET reconstruction algorithm to obtain RSF images (e). With a given measured PET image (f) and calculated RSF images, parameters of (1) can be obtained for GTMo (g) or sGTMo (h) PVC methods.
