Beneficial Effect of Glucose Control on Atherosclerosis Progression in Diabetic ApoE−/− Mice: Shown by Rage Directed Imaging
Cross-sections of aortic tissue stained for H&E (left), RAGE (middle), and macrophages (right) for treated mouse (top row) and untreated mouse (bottom row). The untreated mouse shows a larger lesion size and greater staining for both RAGE and macrophages. Graph depicts results of quantitative histomorphometry showing significantly lower area of cells staining + for both RAGE and macrophages in the treated group.
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