Table of Contents
International Journal of Molecular Imaging
Volume 2015, Article ID 134768, 11 pages
Research Article

Feasibility and Initial Performance of Simultaneous SPECT-CT Imaging Using a Commercial Multi-Modality Preclinical Imaging System

1Graduate School of Medicine, University of Tennessee, Knoxville, TN 37920, USA
2Welch Allyn, Knoxville, TN 37923, USA

Received 28 January 2015; Revised 11 April 2015; Accepted 16 April 2015

Academic Editor: Adriaan A. Lammertsma

Copyright © 2015 Dustin R. Osborne and Derek W. Austin. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Multi-modality imaging provides coregistered PET-CT and SPECT-CT images; however such multi-modality workflows usually consist of sequential scans from the individual imaging components for each modality. This typical workflow may result in long scan times limiting throughput of the imaging system. Conversely, acquiring multi-modality data simultaneously may improve correlation and registration of images, improve temporal alignment of the acquired data, increase imaging throughput, and benefit the scanned subject by minimizing time under anesthetic. In this work, we demonstrate the feasibility and procedure for modifying a commercially available preclinical SPECT-CT platform to enable simultaneous SPECT-CT acquisition. We also evaluate the performance of simultaneous SPECT-CT tomographic imaging with this modified system. Performance was accessed using a 57Co source and image quality was evaluated with phantoms in a series of simultaneous SPECT-CT scans.